https://www.voslab.org/home daily 1.0 2020-05-02 https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1557125151074-UR4K8NSHPO934U2ZYT6O/overview_picture.png home https://www.voslab.org/research daily 0.75 2020-04-18 https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1557126394504-G6O8C9ZS1Z4W7OX37UKJ/overview_picture4.png Research - Research overview The Vos Lab studies how genome organization influences gene expression, specifically to drive cell type specificity. We study how transcription and genome organization are physically coupled using structural biology and biochemistry. This includes X-ray crystallography, cryo-EM, and biophysical approaches. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1587214396166-6A9SUYB1H2EX1LLFWI3I/ncp_PolII_overview_figure.jpg Research - Local genome organization Local genome organization is driven by chromatin and its post-translational modification. We are interested in understanding how molecular machines that modify chromatin influence transcription. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1586284874851-C1VMCFXUZFSN2NP5TDNH/Untitled.jpg Research - Global genome organization Genomes from bacteria to humans are segregated into transcriptionally active and inactive regions through the formation of large, loop-like structures. We are interested in understanding how these loops are formed and how transcription directly affects loop formation and stability. https://www.voslab.org/new-page-1 daily 0.75 2020-04-17 https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1557126047344-BD3C49L62J9X2DL0ZBBM/overview_picture3.png New Page https://www.voslab.org/publications daily 0.75 2026-01-22 https://www.voslab.org/contact daily 0.75 2024-09-10 https://www.voslab.org/people daily 0.75 2026-01-19 https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/046d337c-a258-46f5-9db5-0bfa1057c751/tempImagewBw7cY.jpg people - Make it stand out July 2025 https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1587150305063-VTC7CJFDL2FQLXVT5JZR/DSC_1109.jpg people Seychelle M. Vos, PhD HHMI Freeman Hrabowski Scholar Associate Professor of Biology seyvos@mit.edu B.S. in Genetics, University of Georgia Ph.D. in Molecular and Cell Biology, UC Berkeley Postdoc in Molecular Biology, Max Planck Institute for Biophysical Chemistry Outside of the lab I enjoy backpacking, running, and going on long walks with our pup. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/6da5461f-2b1d-4131-9bfe-1b7c1868d5c6/Funderburg_Quentin_Photo.jpg people - Make it stand out Quentin Funderburg Technical Associate qpf1@mit.edu B.A. in Biology and Chemistry, Williams College Outside of the lab, I enjoy running, hiking, knitting, and playing oboe. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/da3c2f14-6eab-42d6-8364-93ff00112dce/Linkedin+Headshot.jpg people Syed Fardin Ahmed, PhD Postdoctoral Associate sfa97@mit.edu B.S. in Biochemistry, Ithaca College Ph.D. in Structural Biology, Jacobs School of Medicine And Biomedical Sciences, University at Buffalo https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/f2deb08b-3d29-4060-8a66-fe57a29ee236/Mohammed.jpg people - Make it stand out Mohammed Hannan Lab Manager mhannan@mit.edu M. Sc., University of Chittagong https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/f160a0a2-0033-4c67-a36b-402997b4806d/Alexandra.JPG people - Make it stand out Alexandra D’Ordine, PhD Staff Scientist B.S., WPI, Biochemistry and Professional Writing PhD, Brown University, Molecular Biology, Cell Biology, and Biochemistry https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/57e56e00-93de-4a36-9f9e-990e6d6a79c7/headshot.jpg people - Make it stand out Serena Kesha Undergraduate Researcher serena28@mit.edu In my free time I like listening to music, reading, and watching F1. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1630544839950-ME7E7B9X0922PGJ1CK2K/Image%2Bfrom%2BiOS.jpg people Abdallah Mohamed PhD Student, Biology. National Science Foundation Graduate Fellow. aam1@mit.edu B.A. in Biology, Columbia University In my free time, I enjoy watching soccer, listening to music, and going to new restaurants. Science hero: Ramon y Cajal, for his creative and inquisitive approach to neurobiology and his artistic ability to present his work https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1655225264076-EP3VR9GGYOJW9LIZZWYB/Scientist_Vosje_person.jpg people - Make it stand out Meg Rheault Administrative Assistant mrheault@mit.edu https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1adb6e94-afcd-44f1-8dad-6ed3c827a57e/Belen+Pacheco-Fiallos_Outfit1_1.jpg people Belén Pacheco-Fiallos Postdoctoral Associate belpafia@mit.edu B.Sc. in Microbiology and Genetics, University of Vienna, Vienna, Austria M.Sc. in Biochemistry, University of Vienna, Vienna, Austria Ph.D. in Biochemistry and Structural Biology, Research Institute of Molecular Pathology, Vienna, Austria Outside of the lab, I enjoy doing science visual communication and painting using watercolors. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/aca92192-f837-40ee-9570-df4b06ab12b8/TR+Profile+Picture.jpg people - Make it stand out TJ Russell, PhD Postdoctoral Associate tjrus@mit.edu B.S. in Biochemistry, University of Massachusetts Amherst PhD in Biochemistry, Microbiology, and Molecular Biology, The Pennsylvania State University. In my free time, I like to spend time outdoors birdwatching and camping. Science hero: Rachel Carson, for her ability to combine basic research with successful outreach which has resulted in policy changes and the preservation of species! https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/49c78a1c-9ca4-4050-a542-a99590c61634/IMG_6332_boltzi-boi.jpg people - Make it stand out Boltzmann Office Manager, Dogtorate Student Outside the lab I enjoy playing fetch, participating in the Boltzmann Wrestling Foundation (BWF), and going for long walks. Science hero: Ludwig Boltzmann https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/c538bffb-7449-43f5-aae4-248ed24f9eb7/597ca8bb-913a-4cef-bf73-dc33e10a67ad.jpg people - Make it stand out Angelos Pistofidis, PhD Postdoctoral Associate B.S. University College London, Biochemistry M.Sci University College London, Biochemistry PhD. McGill University, Structural and Chemical Biology https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1635457451778-RQNI5AG11K2ZCEWT2FBZ/IMG_8171.jpg people - Make it stand out Roberto Vazquez Nunez, PhD Postdoctoral Associate Former SNSF Postdoctoral Fellow robertvn@mit.edu Basic Biomedical Research Undergraduate and M.S. Biochemistry, National University of Mexico PhD in Biochemistry, University of Lausanne, Switzerland Outside the lab I enjoy riding my bike outdoors, playing soccer, watching TV and playing with my cats https://www.voslab.org/new-page-3 daily 0.75 2023-01-03 https://www.voslab.org/lab-news daily 0.75 2026-01-22 https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/fb8b537f-a84b-4b99-97d6-b3c641ea028e/IMG_0438_Awan_presentation.jpg Lab News - Make it stand out Awan with some of the lab after presenting his summer research work. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/4cea57a5-78ec-4427-b206-a125b5b2aa85/tempImage9FMTn9.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/bb9c8f6d-8942-4d8b-a915-681a8df69b03/IMG_8771+2.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/8c2aa35b-b59a-45a3-8e74-2bc35cb9a61b/IMG_8318+2.jpg Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/0e589303-db4f-4d3e-8279-656cba4a1b6f/DSC_0086.JPG Lab News - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.voslab.org/smithfamilyvideo daily 0.75 2025-08-18 https://www.voslab.org/structure-gallery daily 0.75 2025-08-18 https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1592961005818-GQWW9PHCFK68SERJ86MG/image-asset.png Structure Gallery - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1587214344413-GJFKOUXCE7COOQ7WASNM/ncp_PolII_overview_figure.jpg Structure Gallery - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1557596364901-7Y7STC399VB8PQFIL6AB/MUKB_PARC.jpg Structure Gallery - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/1557599136510-P3ZRD51FVC7S8LLKCJCY/NELF_DSIF.png Structure Gallery - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5cc9f033840b16cd3ed3ca3b/20c650a3-035e-4aaf-913c-15ee3808e106/AGO2_overview_picture.png Structure Gallery - Make it stand out Whatever it is, the way you tell your story online can make all the difference.